Radiation Hybrid DB Release 17
RHdb is a database of raw data used in constructing radiation hybrid maps. This includes STS data, scores, experimental conditions, and extensive cross references.
Radiation hybrid maps are chromosome maps that are calculated from RH score vectors. An RH score vector is the pattern of assay results of a particular STS (marker) on a particular panel. The vector consists of 1's (did amplify) and 0's (did not amplify). Simplistically speaking, the more similar two score vectors are, the closer the markers are on the chromosome.
RH maps are an indispensable alternative to genetic maps as they can include non-polymorphic markers and are also powerful enough to order unresolved genetic clusters of polymorphic STSs.
An international collaborative project has been started which will produce a large number of these hybrids for the human genome. This in turn will allow the generation of a very precise STS map that will be indispensable in the study of multifactorial diseases.
The 17.0 release (1 July 1999) contains 15 panel entries, 182 experimental conditions, 91 maps and 117639 RH entries (91376 different STS) for 5 different species (human, rat, mouse, zebrafish, and maize).
RHdb is available as a flat file from EBI´s ftp servers, but can also be queried and interacted with using a wide range of tools that can be accessed from the RHdb homepage. Several CORBA based utilities are also supported.
Information by: RHdb group
Resources and further information
European Bioinformatics Institute (EMBL-EBI)
Radiation Hybrid DB homepage
RHdb flat file via ftp
External sites are not endorsed by EMBL-EBI