Back to the article
 

Decision tree for the respiration genes

In the decision tree for respiration genes, at the top node there is a total of all 3347 genes, 64 of which are respiration genes. The node splits the gene population on the criteria whether the increase in the expression for a gene at time-point 7 is at least 2.14 times (i.e., if the logarithm base 2 is at least 1.1). It turns out that only 236 genes from the total 3347 have such an increase, and 33 of them are annotated as respiration genes, which is more than a half of the original population of 64. The next split is on criteria whether a gene expression rate does not decrease at time-point 5, which reduces the total population from 236 to 159, while including 31 of the 33 of the respiration genes. Therefore the tree provides us with a rule distinguishing almost half of the respiration genes with 19.5% accuracy. The next level of the decision tree (the increase in the expression at time point 6 is less than 4) allows to distinguish more than one third of the respiration genes (concretely 22 genes) with 25% accuracy from the total list of 88 genes (from the remaining 66 genes 13 are annotated as energy genes different from respiration, and only one of them is a fermentation gene).

Back to the article
 

Direct questions or comments to Bioinformer Editor. This page last modified Friday, 16 July, 1999.
ISSN 1462-1363. More information about the BioInformer.

(c) 1997-1999 EMBL-EBI. All Rights Reserved.