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Geoff Barton
(Head of Structural Database /
Research and Development Team Leader)
E-mail: geoff@ebi.ac.uk |
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I did my first degree in Biochemistry at the University of Manchester, then a Ph.D. supervised by Mike Sternberg at the Department of Crystallography, Birkbeck College, University of London before spending two years as an ICRF Fellow working with Chris Rawlings at the Imperial Cancer Research Fund Labs. in London. From 1989-1997 I was a Royal Society University Research Fellow in the Lab of Molecular Biophysics at the University of Oxford. My research work has centred on applying computational methods to understand the relationship between the amino acid sequence and the three dimensional structure of a protein. I have made contributions to techniques for protein sequence alignment and database searching, protein structure comparison and structure prediction.
From April 1995 until October 1997, I was also Head of Genome Informatics at the Wellcome Trust Centre for Human Genetics. There I set up the computational infrastructure necessary to analyse genomic human DNA to identify candidate genes for specific human diseases. I've published around 45 papers and articles as well as computer programs that are in widespread use, and the 3Dee database of protein structural domains. A full bibliography and details of software and databases are available on my group's web site.
I joined the EBI in October 1997 as Team Leader in Services Research and Development. At EBI my research work on structure prediction and genomic sequence analysis is continuing, but complemented by research on novel database design and the interconnection of heterogenous databases. From January 1998, I added the job of head of the Macromolecular Structure Database (MSD).
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