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Release 2 of TREMBL: a protein sequence database supplementing the SWISS-PROT Protein Sequence Data Bank

Introduction

TREMBL is a protein sequence database supplementing the SWISS-PROT Protein Sequence Data Bank. TREMBL contains the translations of all coding sequences (CDS) present in the EMBL Nucleotide Sequence Database not yet integrated in SWISS-PROT. TREMBL can be considered as a preliminary section of SWISS-PROT. For all TREMBL entries which should finally be upgraded to the standard SWISS-PROT quality, SWISS-PROT accession numbers have been assigned.

Release 2.0 of TREMBL

This TREMBL release is created from the EMBL Nucleotide Sequence Database release 49 and contains 116'379 sequence entries, comprising 31'293'053 amino acids.

TREMBL is split in two main sections; SP-TREMBL and REM-TREMBL:

SP-TREMBL (SWISS-PROT TREMBL) contains the entries (96'757) which should be eventually incorporated into SWISS-PROT. SWISS-PROT accession numbers have been assigned for all SP-TREMBL entries.

SP-TREMBL is organized in 12 subsections:

File

fun.dat

hum.dat

inv.dat

mam.dat

mhc.dat

org.dat

phg.dat

pln.dat

pro.dat

rod.dat

vrl.dat

vrt.dat

Describes

Fungi

Human

Invertebrates

Other Mammals

MHC proteins

Organelles

Bacteriophages

Plants

Prokaryotes

Rodents

Viruses

Other Vertebrates

Number of entries

3108

4541

13269

1740

2307

6705

884

5699

23331

4769

28150

2254


REM-TREMBL (REMaining TREMBL) contains the entries (19'622) that we do not want to include in SWISS-PROT.

Weekly updates of TREMBL

Weekly cumulative updates of TREMBL will be available by anonymous FTP and from the EBI SRS server from the beginning of March 1997 onwards.

Access/Data distribution

TREMBL is available through the FTP or SRS at EBI, and on the SWISS-PROT CD-ROM. SP-TREMBL is searchable on the FASTA server of the EBI and will be soon searchable on the BLITZ server of the EBI.

TREMBL has been prepared by:

Rolf Apweiler, Sergio Contrino, Vivien Junker, Stephanie Kappus, Fiona Lang, Michele Magrane, Maria Jesus Martin, Nicoletta Mitaritonna and Claire O'Donovan at the EMBL Outstation - European Bioinformatics Institute (EBI) in Hinxton, UK;
Amos Bairoch and Alain Gateau at the Medical Biochemistry Department of the University of Geneva, Switzerland.


 

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